Early Identification of Potential Issues Relating to Toxicity
Early investigation of toxicity effects relating to compounds or targets is key to optimizing R&D efforts. Once detected, adverse or toxicity related events need to be linked to specific compounds or targets, with supporting evidence such as IC50 concentrations, kinetic parameters, and exposure measures. Such numerical data is extremely difficult to extract using conventional text search. In contrast, Linguamatics I2E provides fast collation of numerical data from the literature. In addition, I2E can be used to hypothesize indirect relationships, for example by finding mechanisms linking a compound to an adverse effect through a protein or biological process.
Access the application note Text Search and Mining for Safety Toxicity to learn more.