Drug Repositioning by Mining Adverse Event Data in ClinicalTrials.gov

2019 1903:61-72

Su EW

https://link.springer.com/protocol/10.1007/978-1-4939-8955-3_4

Abstract

The protocol below describes an in silico method for drug repositioning (drug repurposing). The data source is ClinicalTrials.gov , which contains about a quarter of a million clinical studies. Mining such rich and clean clinical summary data could be helpful to many health-related researches. Described here is a method that utilizes serious adverse event data to identify potential new uses of drugs and dietary supplements (repositioning).