Publications

Automatically identifying social isolation from clinical narratives for patients with prostate cancer

(2019) 19:43 

Vivienne J Zhu, Leslie A Lenert, Brian E Bunnell, Jihad S Obeid, Melanie Jefferson and Chanita Hughes Halbert.

https://bmcmedinformdecismak.biomedcentral.com/track/pdf/10.1186/s12911-019-0795-y


A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse module

Wang F, Travins J, Lin Z, Si Y, Chen Y, Powe J, Murray S, Zhu D, Artin E, Gross S, Santiago S, Steadman M, Kernytsky A, Straley K, Lu C, Pop A, Struys EA, Jansen EE, Salomons GS, David MD, Quivoron C, Penard-Lacronique V, Regan KS, Liu W, Dang L, Yang H, Silverman L, Agresta S, Dorsch M, Biller S, Yen K, Cang Y, Su SM, Jin S.

J Inherit Metab Dis. 2016 Jul; 39(6): 807–820

PMID: 27469509

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065612/


The promises of quantitative systems pharmacology modelling for drug development

Knight-Schrijver VR, Chelliah V, Cucurull-Sanchez L, Le Novère N.

Comput Struct Biotechnol J. 2016 Sep;14:363-370

PMID: 27761201

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5064996/

Abstract

Recent growth in annual new therapeutic entity (NTE) approvals by the U.S. Food and Drug Administration (FDA) suggests a positive trend in current research and development (R&D) output.